Islet isolation refers to the process of isolating and purifying pancreatic islets from the pancreas for research purposes. Islets are clusters of cells in the pancreas that are responsible for producing and regulating insulin, a hormone that helps regulate blood sugar levels. Islet isolation involves digesting the pancreas tissue, separating the islets from other cells, and purifying them to obtain a highly concentrated sample of islets for study. This process is crucial for studying diabetes, insulin production, and transplantation research.